Fractyl Laboratories has started a sizable clinical trial to test its noninvasive duodenal resurfacing technology as a treatment for insulin resistance in Type 2 diabetes patients. The news comes after the startup garnered a $40 million Series C round from investors including Mithril Capital Management last fall.
Ethicon, the Johnson & Johnson unit devoted to surgical tools, is moving to defend its bariatric surgery territory as a slew of noninvasive medical devices to treat obesity line up to gain approval in the U.S. It will spend $3.2 million on more than 20 clinical trials to examine how early surgical intervention can be used to improve conditions such as obesity and Type 2 diabetes.
Following the theory that Type 2 diabetes is triggered by inflammation, a group of researchers at the German Cancer Research Center concluded that turning off the enzyme Kit prevented a cascade of metabolically linked pathogenic processes.
An international group of investigators led by a scientist at Cedars-Sinai has identified a genetic mutation that protects people from Type 2 diabetes. And they say it makes for a good target for drug developers.
An investigator at Columbia University Medical Center with close ties to Tarrytown, NY-based Armgo Pharma has published new animal data to back up the promise of their clinical-stage diabetes drug Rycal.
Several companies are experimenting with long-term wearable insulin delivery systems that work via continuous subcutaneous infusion to help ease the administration of the medication, thereby making it easier for patients to remain compliant. One such system from startup CeQur recently reported data from a small pilot study.
Investigators at Indiana University School of Medicine have added some fresh preclinical evidence to suggest that the protein Sestrin 3 could one day play a role in treating or preventing Type 2 diabetes.
Just as Eli Lilly and Boehringer Ingelheim's new diabetes drug Jardiance hit store shelves in the U.S., cost-effectiveness watchdogs in the U.K. were considering whether to give it their blessing. The verdict as of Thursday morning? Nay.
Sales of Lipitor, the best-selling drug of all time, may be waning, but litigation over the cholesterol fighter is growing--a lot.
Insulin pumps do a better job of helping control glucose levels in people with Type 2 diabetes than multiple daily injections, according to results from a new study funded by medical device maker Medtronic.