Tag:
preclinical
Latest Headlines
Latest Headlines
CiToxLAB soars in 2012, outpaces preclinical market
French CRO CiToxLAB posted 25% revenue growth in 2012, excellent results that shine compared to the overall results for the preclinical research market.
High blood pressure medicine boosts memories of Alzheimer's-stricken mice
Prazosin, a drug long used to treat high blood pressure, helped prevent mice with Alzheimer's disease symptoms from losing their memories. Researchers at the Imperial College London who performed the study believe that the drug could accomplish the same thing in humans, but not in the way you might expect. The treatment, it seems, reduced brain inflammation.
Study: Amazing early-stage R&D results rarely hold up in big trials
Any regular reader of FierceBiotech knows just how rare it is for a promising drug that produced stellar results in small early studies to march all the way through the clinic without losing its luster or getting snuffed out by an adverse event or lackluster results. Now there's an in-depth trial review that shows clearly just how bad the odds of continued success are.
RNAi positively propels Alnylam cancer vaccine in preclinical study
Alnylam Pharmaceuticals and the company's Dutch research partners say they've reached a big milestone using RNAi to drastically boost the potential of a cancer vaccine under development to generate an immune response.
A cool $1M to fund preclinical work on nanotech/siRNA drug
As funding agencies allocate dollars for translational research, the Pennsylvania Department of Health has earmarked $1 million to advance a nanotechnology-delivered siRNA treatment for cancer toward the clinic.
Hopkins study exposes potential schizophrenia drug target
Johns Hopkins researchers have tied together two culprits behind schizophrenia and believe that their discovery could pave the way to new drugs that combat cognitive impairment caused by the mental disorder.
Nanomedicine busts deadly clots in promising mouse study
The activity of blood platelets has inspired the creation of a nanotherapeutic for dissolving potentially lethal vessel blockages. Tested in mice, the drug-coated nanoparticles targeted diseased blood vessels and reduced clots with a relatively small amount of active drug.
Rotund rodents shed pounds with new vaccine
Chubby mice quickly shed 10% of their body weight when injected with modified somatostatin, a peptide hormone.
Researchers cure Type 1 diabetes in mice
A dose of antibodies, a bone marrow transplant and treatment with pancreas growth factor helped cure late-stage Type 1 diabetes in mice, researchers have found.
Pfizer stays in the autism drug chase
In a mouse study, the drug giant's experimental depression drug GRN-529 reduced visible signs of autism in mice, Bloomberg reported.
