Johnson & Johnson was cautiously lauded for its clinical trial data-sharing initiative, but Roche's project was pilloried. Now Novartis has joined its Swiss peer in rolling out an underwhelming transparency program.
Clinical trial data collection has evolved slowly over the past two decades from site visits and paper questionnaires to telemedicine and electronic patient reported outcomes. The transition is far from complete though, with the likes of CamNtech and Medidata now looking to bring wearable computers to clinical trials.
After investigators tracked a rising rate of blood clots among leukemia patients in ongoing clinical studies, the biotech slammed the brakes on new trial enrollment and rolled out a lower dosing schedule for current participants.
Using lipids derived from grapefruits, researchers at the University of Louisville have created nanoparticles for drug delivery that are less toxic to both people and the environment and may offer a less expensive alternative to synthetic materials.
Less than a week after securing a CE mark for its DESolve drug-eluting stent, Elixir Medical reported successful results in a pivotal trial of the same device, which should reach the market by the end of this year.
Novaliq's drug delivery platform that helps poorly soluble drugs dissolve more easily helped the company pull in a sizable funding round, which in turn could push its lead dry eye product into Phase I trials.
Another clinical trial search engine rolled out this week with talk of making it easier for patients to find studies, and vice versa. But the website, MyClinicalTrialLocator, finds itself in an increasingly congested market filled with CROs, in-house Big Pharma platforms and niche players.
Microsoft is applying its database know-how to the problem of the lack of minority participation in clinical trials. The tech giant is turning data gathered by the National Minority Quality Forum into a searchable national archive to support the diversification of trials.
GlaxoSmithKline has long been the Big Pharma standard-bearer for open clinical trial data, and now the drugmaker has thrown its support behind the AllTrials campaign, a U.K. initiative to register and publicize all studies.
As India's government churns over the idea of tightening clinical trial regulations, a private industry group is entering the fold and launching a committee designed to improve transparency.