The growing pool of genomics data and bioinformatics capabilities present new opportunities to improve outcomes for cancer patients. Yet without coordinated, multidisciplinary collaborations, the industry risks failing to take full advantage, researchers warned this week.
Perjeta is now the first cancer drug approved to treat patients before surgery. Developed by Roche's Genentech unit, and already approved for women with advanced HER2-positive breast cancer, Perjeta can now reach a huge new group of patients at early stages of the disease.
You might call Perjeta a guinea pig. The new breast cancer drug from Roche's Genentech unit could soon become the first approved for cancer patients before they've had surgery. It would also be the first approved under new FDA guidelines for speeding cancer drugs to patients with early-stage disease.
Roche's study looked at Perjeta in combination with Roche's Herceptin and chemotherapy, compared with Herceptin and chemo alone. Patients on Perjeta and Herceptin saw statistically significant improvements in tumor size compared with those in the Herceptin-only arm, the FDA reveiewers noted.
AstraZeneca has sponsored a web portal that features videos of breast-cancer patient testimonials, becoming one of the latest drugmakers to provide online content to target patient populations.
To win over U.K. cost-effectiveness gatekeepers, Novartis cut Afinitor's price. Unfortunately for the Swiss drugmaker, it didn't work. The National Institute for Health and Care Excellence still turned down a new use for the drug in HER2-negative breast cancer.
After a recent U.S. Supreme Court decision shielded Myriad Genetics' genetic data on breast cancer from disclosure, a nonprofit coalition called Free the Data! has launched a campaign to open troves of molecular information about the widespread tumors with the help of a big data software outfit called Syapse.
South Korean researchers have made progress with a microwave tomography imaging (MTI) system for detecting breast tumors, seeking an alternative that could be more accurate than mammography.
Two breast cancer drugs could get a boost from new expert advice. The U.S. Preventive Services Task Force now recommends that doctors offer the drugs--tamoxifen and raloxifene, a.k.a. Eli Lilly's ($LLY) Evista--to high-risk patients to prevent the disease.
Pfizer won coveted "breakthrough" status from the FDA for its experimental breast cancer drug palbociclib after impressive interim results from a mid-stage study.